Using Apache's mod_rewrite, it is possible to give Bugzilla pretty URLs for certain pages.
/assigned-to/me@example.com/
lists all bugs that are assigned to the specified email address
/reported-by/me@example.com/
lists all bugs that were reported by the specified email address
/new-bug/
redirects to the page listing all products to create a new bug report about
/new-bug/Product Name/
shows the form to create a new bug for the specified product
/graph/
shows our Open Bugs vs. Resolved Bugs graph
/open/
lists all open (new/assigned/etc.) bugs
/unassigned/
lists all unassiged (i.e. just the 'new' status) bugs
/fixed/
lists all fixed (resolved-fixed) bugs
/123/
shows bug #123